Penn has considerable depth in science studies. The Department of Philosophy is especially strong in the philosophy of science, the relations between the history of philosophy and the history of science, and the history of the philosophy of science.

Faculty working in these fields include: Cristina Bicchieri, game theory and philosophy of social science; Karen Detlefsen, early modern philosophy and biology; Zoltan Domotor, philosophy of physics and the kinematics of belief change; Gary Hatfield, early modern philosophy and science, philosophy and history of psychology; Susan Schneider, metaphysics and the laws of nature; Scott Weinstein, logic and topics in philosophy of science; and Michael Weisberg, philosophy of biology and chemistry, general philosophy of science.

In addition, William Ewald (Law School) teaches history and philosophy of mathematics, Steve Kimbrough (Wharton) teaches modeling, machine learning, and induction, Alan Kors and Ann Moyer (Department of History) offer courses in early modern intellectual history and history of science, and in History and Sociology of Science (HSS) Mark Adams teaches history of biology, Henrika Kuklick history of the human sciences, Susan Lindee history of genetics, and John Tresch history of the human sciences.

The Philosophy Program permits up to three (approved) courses (toward the fifteen course requirement for doctoral students) to be taken outside philosophy (e.g., in HSS, History, or a science), and students may explore the possibility of more extensive graduate work in a science while in the doctoral program. The Departments of History and Sociology of Science and of Sociology offer training in other fields in science studies. Those interested primarily in sociology should contact HSS or Sociology.